20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4388 | PHTPP | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
PHTPP is a selective ERβ antagonist. | |||
TN1052 | Lindleyin | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
Lindleyin is a novel phytoestrogen and might trigger many of the biological responses evoked by the physiological estrogens. | |||
T15249 | Estrogen receptor modulator 1 | Estrogen Receptor/ERR | |
Estrogen receptor modulator 1 causes regression of Tamoxifen-resistant, hormone-independent xenograft tumors. Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM) (pIC50: 0.4... | |||
T13768 | (+)-Medicarpin | Estrogen/progestogen Receptor | |
(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium flo... | |||
T5S0543 | Isocurcumenol | Apoptosis , Estrogen Receptor/ERR , Reductase | |
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT). | |||
T3665 | Tectoridin | Shekanin | Estrogen Receptor/ERR , Reductase |
Tectoridin (Shekanin) possesses an estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin an... | |||
T3855 | Tracheloside | Estrogen Receptor/ERR , Phosphorylase | |
Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml). | |||
T16566 | Propyl pyrazole triol | PPT | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Propyl pyrazole triol (PPT) is a selective agonist of estrogen receptor alpha. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: ... | |||
T7904 | SR 19881 | Estrogen/progestogen Receptor | |
SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay). | |||
T8984 | FLTX1 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
FLTX1 is a fluorescent derivative of Tamoxifen, designed to efficiently target and label intracellular Tamoxifen-binding sites (estrogen receptors) both under permeabilized and non-permeabilized conditions. Additionally,... | |||
T0593 | XCT790 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Autophagy | |
XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα). | |||
TQ0295 | Coumestrol | Estrogen Receptor/ERR | |
Coumestrol that existed in soybean products suppresses the proliferation of ES2 cells (IC50: 50 μM). It exhibits activities against neurological disorders, cancers and autoimmune diseases. | |||
T15364 | G-1 | Estrogen Receptor/ERR , GPR | |
G-1 is a nonsteroidal, high-affinity and selective GPR30 agonist (Ki: 11 nM). | |||
T7389 | G15 | Estrogen Receptor/ERR | |
G15 is a cell-permeable non-steroidal antagonist of GPER (Ki = 20 nM) | |||
T14987 | CMP8 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, res... | |||
T5531 | GSK-4716 | Estrogen Receptor/ERR | |
GSK4716 is an ERRβ/γ agonist (IC50 = 2 µM) that can activate the receptor with similar potency as the protein ligand | |||
T3975 | AZD9496 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor | |
AZD9496 is an orally available selective estrogen receptor(ERα) antagonist, with potential antineoplastic activity. | |||
T3958 | WAY-200070 | WAY 200070 | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
WAY-200070 is a specific agonist of estrogen receptor β (ERRβ, IC50: 2.3 nM). | |||
T13542 | α-Zearalenol | Estrogen Receptor/ERR | |
α-Zearalenol is one of the major metabolites of Zearalenone. α-Zearalenol has structural analogy to estrogen, thus α-Zearalenol can bind to estrogen receptors (ERs). | |||
T1216 | Diethylstilbestrol | Stilbestrol,DES | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Diethylstilbestrol (DES) is used in the treatment of menopausal and postmenopausal disorders. |